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相關學術文章:
Histologic evaluation of bone healing of adjacent alveolar sockets grafted with bovine and porcine-derived bone: a comparative case report in humans

在相鄰的缺牙傷口使用牛骨和豬骨的移植物填補後,骨癒合的組織學評估:人類病例報告的比較
 

Renzo Guarnieri1,*, Patricia DeVilliers2, Maurizio Grande3, Luigi Vito Stefanelli1, Stefano Di Carlo4 and Giorgio Pompa5

出處:Regenerative Biomaterials, 2017, 1–4

摘要:
ABSTRACT

目的:
Purpose

To evaluate and compare histomorphometrically the bone response to two xenografts, one bovine and the other porcine, grafted in adjacent extraction sockets in a human.
將兩種異種移植物(一種取自牛,另一種取自豬) 移植至拔牙後的傷口,評估和比較兩種補骨材在六個月後組織型態學上的反應。
 

材料跟方法:
Materials and Methods

In this case report, two adjacent maxillary premolars were extracted, and the sockets were filled with two different xenogeneic bone substitutes (first premolar with bovine bone, and second premolar with porcine bone) to counteract post-extraction volume loss. Following 6 months bone core specimens were harvested during the placement of implants at the regenerated sites.
在這病例報告中,將兩顆相鄰的小臼齒拔除,並填入兩種不同的異種移植物(第一小臼齒填入牛骨,第二小臼齒填入豬骨),以抵抗拔牙後造成的骨流失。六個月後,取植入補骨材的再生骨核心樣本。 
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結果:
Results
 
Histomorphometrically, for the bovine xenograft the percentage of newly formed bone (osteoid) was 26.85%, the percentage of the residual graft material was 17.2% and the percentage of connective tissue 48.73%, while for the porcine xenograft, newly formed bone (osteoid) represented 32.19%, residual graft material was 6.57% and non-mineralized connective tissue was 52.99%.
組織型態學方面,對於牛異種移植物,新骨形成佔26.85%,剩餘移植物佔17.2%,結締組織佔48.73%;豬異種移植物,新骨形成佔32.19%,剩餘移植物佔6.57%,非礦化結締組織佔52.99%。
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結論:
Histological results indicated that both biomaterials assessed in this study as grafts for socket preservation technique are biocompatible and osteoconductive. Bovine bone derived demonstrated to be less resorbable than porcine bone derived. Both xenogenic biomaterials did not interfere with the normal bone reparative processes.
組織學結果顯示,本研究中評估的生物材料均為用來填補拔牙後傷口的移植物,皆具有生物相容性和骨傳導性。另證實牛骨比豬骨需要更長的再吸收時間。兩者異種移植物皆不會干擾正常的骨修復過程。
 
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